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The Lab Notebook

Saturday 24 October 2026 · No. 3

Top Story The Gulf

Oil Jumps Above $114 as Houthi Attacks on Saudi Arabia Continue

Aramco moves staff out of its Dhahran headquarters as Brent heads for a third weekly gain.

🧵 New to this story? Read the story so far →
📍 Persian Gulf · Saudi Arabia, Iran, Yemen

Brent crude, the benchmark price for oil traded around the world, rose 3.59% to $117.20 a barrel at 7:58pm UAE time on Friday 23 October. Earlier in the day it had traded about 1.1% higher at $114.5. US crude (WTI) climbed 3.57% to $103. Brent was on track for a third straight weekly gain.

The driver was a new wave of attacks on Saudi Arabia. Over 48 hours the Houthis, an armed group from Yemen, claimed strikes on the Saudi Defence Ministry headquarters in Riyadh, King Fahd International Airport in Dammam, Abha International Airport and an Aramco site in Yanbu. These are Houthi claims; the report does not confirm them independently. Two people died and several were injured in the attacks at Dammam airport.

Saudi Aramco, the state oil company, then evacuated its Dhahran headquarters, the first such evacuation since the Iran war began in late February. The shipping lane matters too. The UK's maritime trade centre counted 10 attacks on commercial vessels in and near the Strait of Hormuz in the week to 19 October, and called October the worst month for such attacks since March.

For grown-ups: sources

World Russia and Ukraine

Putin Agrees in Principle to Restart Three-Way Ukraine Talks

Russia says talks with the US and Ukraine could resume after 10 November.

🧵 New to this story? Read the story so far →
Talks, again123
The three sides last met in Geneva in February.

Russian President Vladimir Putin met US envoy Steve Witkoff in St. Petersburg on Wednesday 21 October for about three hours. Afterwards the Kremlin's foreign affairs adviser, Yuri Ushakov, said Putin agreed “in principle” to resume trilateral talks with the US and Ukraine after 10 November. Trump's son-in-law Jared Kushner joined by video link.

Ushakov said the talks would focus on building a security system for Russia and Ukraine after the conflict ends. Earlier rounds, in Abu Dhabi in January and February and in Geneva in February, produced little progress beyond prisoner exchanges. Witkoff said there was “some degree of momentum”. Russia also freed American Stephen Hubbard, a retired teacher imprisoned on mercenary charges, which Witkoff called a goodwill gesture. Putin also said he was ready to consider restoring US-Russia economic ties, and Witkoff thanked him for lifting Russia's ban on diesel exports.

Ukraine's position differs. President Volodymyr Zelenskyy said a freeze in the fighting is the “minimum” Russia must accept, and that only a leaders' summit can break the impasse. The fighting goes on: Russian strikes in Kyiv killed three people and wounded 12, and Russia's Defense Ministry said it intercepted 373 Ukrainian drones overnight. Ukraine launched more than 1,000 drones at Russia in one of its largest attacks of the war, and an oil export terminal in St. Petersburg caught fire.

The US role is under strain. Witkoff met Zelenskyy and European leaders in Oslo on Tuesday and plans to return there; Norway's prime minister, Jonas Gahr Støre, said Russia may be looking for diplomatic options. On Tuesday Trump pressed Zelenskyy to make a deal and said the US had gotten “absolutely nothing back” from Ukraine. Trump had said on 11 October that Russia and Ukraine agreed to an energy-infrastructure ceasefire, but attacks have continued.

🗺️ Where in the world?

📍 St. Petersburg · Russia, Ukraine
For grown-ups: sources

Science & Tech Space

Perseverance Passes Opportunity's Driving Record on Mars

A rover that mostly steers itself has driven 28.10 miles in about five and a half years.

A long drive
Opportunity's record stood at 28.06 miles.

NASA's Perseverance rover passed the distance record for driving on another world on 11 October. Its odometer reached 28.10 miles (45.22 km) on its 2,006th Martian day, just beyond the 28.06 miles (45.16 km) driven by Opportunity. Perseverance took about five and a half years. Opportunity took nearly 15 years.

The difference is self-driving. More than 90% of Perseverance's distance was covered with AutoNav, its autonomous navigation system, against about 5% for Opportunity and its twin Spirit. The mission's original plan called for no more than 12.4 miles (20 km) of driving. The rover has also collected 29 rock and regolith samples.

The first mission extension began in October 2026 and runs to about the end of 2028. Next, the rover heads for Rainbow Falls, a block of ancient crust about 328 feet (100 m) wide, after science at the crater rim at Lac de Charmes and the Idubi area.

NASA put the record in context. The drive that broke it was 299.6 feet (91.31 m), and the longest single-day drive was up to 1,351 feet (412 m). Perseverance analyses 600,000 measurement points each time it looks ahead, compared with 20 for Sojourner. Spirit drove 4.8 miles and Curiosity more than 23.65 miles. On the Moon, Apollo 17 covered 22.2 miles and the Soviet Lunokhod 2 covered 24.2 miles; Perseverance has passed both. The mission team thinks the rover could eventually more than double the distance it has already traveled. Sojourner, the first Mars rover, drove about 330 feet (100 m) in 1997, and Opportunity operated for 5,111 sols.

🗺️ Where in the world?

📍 Jezero Crater, Mars
For grown-ups: sources

Climate & Environment Wildlife

Wildlife Populations Down 73% on Average, With Some Recoveries

WWF's Living Planet Report 2026 tracks vertebrate animals since 1970.

Wildlife, 1970 to 2022
Weighted averages, not a count of animals.

The Living Planet Index, produced by the Zoological Society of London, follows 35,803 population trends of 5,790 vertebrate species (animals with backbones) from 1970 to 2022. Its headline number is a 73% average decline. That figure is a weighted average of population change, not a loss of 73% of individuals or species.

The detail matters. Across the data, 50% of populations were in decline, 7% were stable and 43% were increasing. Freshwater species fared worst, falling 85%, and Latin America and the Caribbean saw the steepest regional decline, at 95%.

There is also good news. Green sea turtles, bluefin tuna, tigers and southern African elephants have recovered in places, which WWF credits to conservation. A survey estimating about 183,000 giant tortoises on Aldabra in Seychelles points the same way: heavy hunting in the 19th century left fewer than 1,000, but the island became a strict nature reserve in 1981, invasive goats were removed in 2012, and it became a UNESCO World Heritage Site in 1982. The UN Biodiversity Conference in Yerevan, Armenia, later this month will review countries' progress on halting nature loss.

Another study this week suggests honeybees can crowd out wild pollinators. On Giannutri, a small Italian island, researchers temporarily removed honeybee hives, and nectar and pollen levels surged, letting wild bees forage more, National Geographic reported of the Current Biology study.

🗺️ Where in the world?

📍 Yerevan · Armenia
For grown-ups: sources

Health Cancer Research

Personalised mRNA Vaccine Cuts Melanoma Return Risk by 42% in Trial

Moderna and Merck's vaccine was given with the immunotherapy Keytruda.

Cancer vaccine trial
Results were shown at ESMO in Madrid.

Melanoma is a serious type of skin cancer. This week Moderna and Merck released results from a late-stage trial of an experimental personalised mRNA vaccine, given together with the immunotherapy drug Keytruda. Reports say it lowered the risk of melanoma returning by 42% in a trial of about 1,100 patients.

The results were presented at ESMO, a cancer conference, in Madrid. STAT reported that the data came out before the scheduled presentation. Its authors called the early release an embargo violation on the eve of the conference; an embargo asks journalists to wait until an agreed time before reporting results.

A 42% lower risk is a relative figure: it compares the chance of the cancer returning in one group of patients with the chance in another. This is a company-reported result, not yet a treatment patients can get. Independent checking of the full data, and later approval decisions, will matter before anyone can say how widely the vaccine could be used.

It was not the only vaccine news this week. On 7 October MimiVax and Roswell Park reported Phase 2b results for a vaccine called SurVaxM, which they said showed a significant survival benefit for newly diagnosed glioblastoma patients aged 65 and under. On 8 October Mount Sinai announced a five-year, $20.7 million agreement to develop next-generation respiratory vaccines, starting with an H5N1 flu vaccine prototype.

🗺️ Where in the world?

📍 Madrid · Spain
For grown-ups: sources

History & Geography Early Humans

South African Fossils Suggest Homo erectus Lived There Earlier

A skull fragment from Drimolen is about 2 million years old.

AGE OF ADULT H. ERECTUS FOSSILS Millions of years old

Drimolen is in South Africa; Dmanisi is in Georgia.

Researchers led by Dr Jesse Martin of La Trobe University described 18 hominin fossils from Drimolen Main Quarry in South Africa, in the journal Annals of Human Biology. Hominins are humans and their close extinct relatives. Drimolen lies in the Cradle of Humankind, and the site was discovered in 1992 and excavated through 2019. An earlier H. erectus fossil from Drimolen, DNH 134, came from a child aged 2 to 4.

The key find is an adult Homo erectus skull fragment, catalogued as DNH 127, about 2 million years old. That is about 200,000 years older than adult H. erectus fossils from Dmanisi, Georgia, which date to about 1.8 million years ago. The team says this supports the idea that the species reached southern Africa earlier than thought.

H. erectus was rare at Drimolen. Another hominin, Paranthropus robustus, outnumbered it there by more than 10 to 1. Between about 2 and 1.8 million years ago that species developed larger teeth and stronger chewing muscles, and its brain was only slightly larger than a chimpanzee's.

🗺️ Where in the world?

📍 Drimolen, Cradle of Humankind · South Africa, Georgia
For grown-ups: sources

Did you know?

Opportunity, the rover whose distance record Perseverance has passed, explored Mars from 2004 to 2018.

Explainer

How a personalised cancer vaccine works

Unlike a vaccine against a virus, a cancer vaccine is meant to help the body attack cells that have already turned cancerous. Tumours carry changes, called mutations, that healthy cells lack. A personalised vaccine is designed from a patient's own tumour so that the immune system learns to recognise those changes.

An mRNA vaccine delivers instructions for cells to make particular proteins so the immune system can practise on them. Keytruda is an immunotherapy: a drug that helps the immune system fight cancer. Giving the two together is meant to train the immune system and then keep it active.

Discuss

DISCUSS

Why might a company-reported trial result need independent checking?

Why can an average hide both bad news and good news, as the wildlife figure does?

Why might a rover that steers itself matter more the farther it is from Earth?

In brief

More news

  • India: Delhi's air stayed “poor” on Friday, with an air quality index of 223, and winter curbs have begun.
  • Space: A catalogue of 2,884 exploding stars hints that dark energy, the force driving the universe's expansion, may change over time.
  • Europe: Protests over living costs, schools and housing have spread across France, Italy, Spain, Portugal and Albania.
  • UK: Inflation rose to 3.5% in the year to September, from 3.1% in August.

New words

Words from this issue

Hominin
A human or one of our close extinct relatives. Today: 18 hominin fossils were described from Drimolen.
Weighted average
An average in which some values count for more than others. Today: the 73% wildlife decline is a weighted average of population change.
mRNA
A molecule that carries instructions for making a protein. Today: a personalised mRNA vaccine is being tested against melanoma.
Autonomy
The ability to act without constant instruction. Today: Perseverance used its AutoNav system for more than 90% of its driving.

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